3,981 research outputs found
Tubewell transfer in Gujarat: A study of the GWRDC approach
Tube wells / Privatization / Groundwater management / Economic aspects / Operations / Maintenance / Equity / Farmers? attitudes / Policy
Innate immunity and neuroinflammation
Copyright © 2013 Abhishek Shastri et al. This is an open access article distributed under the Creative Commons Attribution
License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Inflammation of central nervous system (CNS) is usually associated with trauma and infection. Neuroinflammation occurs in close relation to trauma, infection, and neurodegenerative diseases. Low-level neuroinflammation is considered to have beneficial effects whereas chronic neuroinflammation can be harmful. Innate immune system consisting of pattern-recognition receptors, macrophages, and complement system plays a key role in CNS homeostasis following injury and infection. Here, we discuss how innate immune components can also contribute to neuroinflammation and neurodegeneration
An Exploratory Study of COVID-19 Misinformation on Twitter
During the COVID-19 pandemic, social media has become a home ground for
misinformation. To tackle this infodemic, scientific oversight, as well as a
better understanding by practitioners in crisis management, is needed. We have
conducted an exploratory study into the propagation, authors and content of
misinformation on Twitter around the topic of COVID-19 in order to gain early
insights. We have collected all tweets mentioned in the verdicts of
fact-checked claims related to COVID-19 by over 92 professional fact-checking
organisations between January and mid-July 2020 and share this corpus with the
community. This resulted in 1 500 tweets relating to 1 274 false and 276
partially false claims, respectively. Exploratory analysis of author accounts
revealed that the verified twitter handle(including Organisation/celebrity) are
also involved in either creating (new tweets) or spreading (retweet) the
misinformation. Additionally, we found that false claims propagate faster than
partially false claims. Compare to a background corpus of COVID-19 tweets,
tweets with misinformation are more often concerned with discrediting other
information on social media. Authors use less tentative language and appear to
be more driven by concerns of potential harm to others. Our results enable us
to suggest gaps in the current scientific coverage of the topic as well as
propose actions for authorities and social media users to counter
misinformation.Comment: 20 pages, nine figures, four tables. Submitted for peer review,
revision
Energy-irrigation nexus in South Asia: Improving groundwater conservation and power sector viability
Tube wells / Energy consumption / Costs / Electricity supplies / Groundwater irrigation / Water policy / Pumps / Water rates
Hemispheric lateralisation and immune function: A systematic review of human research
This is the post-print version of the final paper published in Journal of Neuroimmunology. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. Copyright @ 2011 Elsevier B.V.Past studies examined relationships between hemispheric lateralisation (HL) and immune system functioning. However, there has been no up-dated systematic review of this research area. This article reviews relevant published studies, evaluates study quality and effect sizes. Eleven studies were selected: three revealing a relationship between weaker left hemisphere function and poorer immune function, three describing a relationship between weaker right hemisphere function and stronger immune functioning, and five describing both relationships. Mean effect-size of the studies was r = 0.536 (range 0.280–0.866). Collectively, studies point at left-HL and stronger immunity relationships. Limitations, mechanisms and clinical implications are discussed
Huntington's disease: An immune perspective
Copyright © 2011 Annapurna Nayaketal. This article has been made available through the Brunel Open Access Publishing Fund.Huntington's disease (HD) is a progressive neurodegenerative disorder that is caused by abnormal expansion of CAG trinucleotide repeats. Neuroinflammation is a typical feature of most neurodegenerative diseases that leads to an array of pathological changes within the affected areas in the brain. The neurodegeneration in HD is also caused by aberrant immune response in the presence of aggregated mutant huntingtin protein. The effects of immune activation in HD nervous system are a relatively unexplored area of research. This paper summarises immunological features associated with development and progression of HD.U. Kishore acknowledges funding via BRIEF and Brunel University’s strategic funding for the Centre of Infection, Immunity and Disease Mechanisms
The cosmological gravitational wave background from primordial density perturbations
We discuss the gravitational wave background generated by primordial density
perturbations evolving during the radiation era. At second-order in a
perturbative expansion, density fluctuations produce gravitational waves. We
calculate the power spectra of gravitational waves from this mechanism, and
show that, in principle, future gravitational wave detectors could be used to
constrain the primordial power spectrum on scales vastly different from those
currently being probed by large-scale structure. As examples we compute the
gravitational wave background generated by both a power-law spectrum on all
scales, and a delta-function power spectrum on a single scale.Comment: 8 Page
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